Ischemic nephropathy: Detection and therapeutic intervention

TGF-1-induced-EMT and therapeutic intervention in Diabetic Nephropathy

Ischemic nephropathy - pathogenesis and treatment.

In this review paper we would like to summarized the current knowledge concerning the  pathogenesis and treatment of ischemic nephropathy. Epidemiological data suggest that the prevalence of ischemic nephropathy increases, especially among older individuals. The pathogenesis of this disease is more complex than just narrowing of the renal artery due to atherosclerosis. Renin-angiotension s...

Renovascular Hypertension and Ischemic Nephropathy

The major issues in approaching patients with renal artery stenosis relate to the role of renal artery stenosis in the management of hypertension, ie, “renovascular hypertension,” and to the potential for vascular compromise of renal function, ie, “ischemic nephropathy.” Ever since the original Goldblatt experiment in 1934, wherein experimental hypertension was produced by renal artery clamping...

Renovascular hypertension and ischemic nephropathy.

Renovascular disease remains among the most prevalent and important causes of secondary hypertension and renal dysfunction. Many lesions reduce perfusion pressure including fibromuscular diseases and renal infarction, but most are caused by atherosclerotic disease. Epidemiologic studies establish a strong association between atherosclerotic renal-artery stenosis (ARAS) and cardiovascular risk. ...

Immunopathogenic Mechanism and Therapeutic Intervention in an Experimental Murine Model of Membranous Nephropathy